Emerging role of angiotensin type 2 receptor (AT2R)/Akt/NO pathway in vascular smooth muscle cell in the hyperthyroidism.

Hyperthyroidism is characterized by increased vascular relaxation and decreased vascular contraction and is associated with augmented levels of triiodothyronine (T3) that contribute to the diminished systemic vascular resistance found in this condition. T3 leads to augmented NO production via PI3K/A...

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Bibliographic Details
Main Authors: Maria Alícia Carrillo-Sepúlveda, Graziela S Ceravolo, Cristina R Furstenau, Priscilla de Souza Monteiro, Zuleica Bruno-Fortes, Maria Helena Carvalho, Francisco R Laurindo, Rita C Tostes, R Clinton Webb, Maria Luiza M Barreto-Chaves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634851?pdf=render