PIN1 protects auditory hair cells from senescence via autophagy

Background Age-related hearing loss is an increasing sensorineural hearing loss. But the pathogenesis of ARHL has not been clarified. Herein, we studied the role and significance of PIN1 in regulating autophagy activity in senescence HEI-OC1cells and HCs. Methods and Results C57BL/6 mice and HEI-OC1...

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Bibliographic Details
Main Authors: Zhe Lv, Yanzhuo Zhang, Huan Cao, Qingjuan Liu, Xiaojuan Feng, Huan Yin, BaoShan Wang
Format: Article
Language:English
Published: PeerJ Inc. 2022-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14267.pdf