Validation of SNP allele frequencies determined by pooled next-generation sequencing in natural populations of a non-model plant species.

Sequencing of pooled samples (Pool-Seq) using next-generation sequencing technologies has become increasingly popular, because it represents a rapid and cost-effective method to determine allele frequencies for single nucleotide polymorphisms (SNPs) in population pools. Validation of allele frequenc...

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Bibliographic Details
Main Authors: Christian Rellstab, Stefan Zoller, Andrew Tedder, Felix Gugerli, Martin C Fischer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3820589?pdf=render