Mutation patterns of resistance genes for macrolides, aminoglycosides, and rifampicin in non-tuberculous mycobacteria isolates from Kenya [version 5; peer review: 2 approved, 1 not approved]

Background: Non-tuberculous mycobacteria (NTM) treatment constitutes a macrolide-based antibiotic regimen in combination with aminoglycosides for Rapid-Growing Mycobacteria (RGM), and rifampicin for Slow-Growing Mycobacteria (SGM). Mutations in the anti-NTM drug target regions promote NTM evolution...

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Bibliographic Details
Main Authors: Wallace Bulimo, Marianne Mureithi, Frank Onyambu, Zakayo Mwangi, Grace Naeku
Format: Article
Language:English
Published: F1000 Research Ltd 2023-04-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/11-962/v5