Intracerebral but Not Peripheral Infection of Live <i>Porphyromonas gingivalis</i> Exacerbates Alzheimer’s Disease Like Amyloid Pathology in APP-TgCRND8 Mice
The impact of oral microbial dysbiosis on Alzheimer’s disease (AD) remains controversial. Building off recent studies reporting that various microbes might directly seed or promote amyloid β (Aβ) deposition, we evaluated the effects of periodontal bacteria (<i>Porphyromonas gingivalis, Trepone...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/6/3328 |