Detect the early-warning signals of diseases based on signaling pathway perturbations on a single sample

Detect the early-warning signals of diseases based on signaling pathway perturbations on a single sample

Abstract Background During the pathogenesisof complex diseases, a sudden health deterioration will occur as results of the cumulative effect of various internal or external factors. The prediction of an early warning signal (pre-disease state) before such deterioration is very important in clinical...

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Bibliographic Details
Main Authors: Yanhao Huo, Geng Zhao, Luoshan Ruan, Peng Xu, Gang Fang, Fengyue Zhang, Zhenshen Bao, Xin Li
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
Pre-disease state
Early warning signals
Single sample
Signal perturbation
Signaling pathway
Online Access:https://doi.org/10.1186/s12859-021-04286-2

Internet

https://doi.org/10.1186/s12859-021-04286-2

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