What Is the Exact Contribution of <i>PITX1</i> and <i>TBX4</i> Genes in Clubfoot Development? An Italian Study

What Is the Exact Contribution of <i>PITX1</i> and <i>TBX4</i> Genes in Clubfoot Development? An Italian Study

Congenital clubfoot is a common pediatric malformation that affects approximately 0.1% of all births. 80% of the cases appear isolated, while 20% can be secondary or associated with complex syndromes. To date, two genes that appear to play an important role are <i>PTIX1</i> and <i>...

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Bibliographic Details
Main Authors: Anna Monica Bianco, Giulia Ragusa, Valentina Di Carlo, Flavio Faletra, Mariateresa Di Stazio, Costantina Racano, Giovanni Trisolino, Stefania Cappellani, Maurizio De Pellegrin, Ignazio d’Addetta, Giuseppe Carluccio, Sergio Monforte, Antonio Andreacchio, Daniela Dibello, Adamo P. d’Adamo
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Genes
Subjects:
clubfoot
congenital talipes equinovarus
congenital malformation
<i>TBX4</i>
<i>PITX1</i>
Online Access:https://www.mdpi.com/2073-4425/13/11/1958

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https://www.mdpi.com/2073-4425/13/11/1958

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