Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations
Abstract Background The discovery of CRISPR-based gene editing and its application to homing-based gene drive systems has been greeted with excitement, for its potential to control mosquito-borne diseases on a wide scale, and concern, for the invasiveness and potential irreversibility of a release....
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12915-020-0759-9 |