Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

Abstract Background The discovery of CRISPR-based gene editing and its application to homing-based gene drive systems has been greeted with excitement, for its potential to control mosquito-borne diseases on a wide scale, and concern, for the invasiveness and potential irreversibility of a release....

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Bibliographic Details
Main Authors: Héctor M. Sánchez C., Jared B. Bennett, Sean L. Wu, Gordana Rašić, Omar S. Akbari, John M. Marshall
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-020-0759-9