Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA

Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA

In this study, the impact of different delivery systems on the cytokine-inducing, antiproliferative, and antitumor activities of short immunostimulatory double-stranded RNA (isRNA) was investigated. The delivery systems, consisting of the polycationic amphiphile 1,26-bis(cholest-5-en-3-yloxycarbonyl...

Full description

Bibliographic Details
Main Authors: Ali Bishani, Darya M. Makarova, Elena V. Shmendel, Mikhail A. Maslov, Aleksandra V. Sen‘kova, Innokenty A. Savin, Daniil V. Gladkikh, Marina A. Zenkova, Elena L. Chernolovskaya
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
immunostimulatory RNA
cationic liposomes
lipoconjugates
cytokine-inducing activity
antitumor activity
IFN alpha
Online Access:https://www.mdpi.com/1999-4923/15/9/2184

Internet

https://www.mdpi.com/1999-4923/15/9/2184

Similar Items