Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody

Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody

Abstract Photoimmunotherapy (PIT) is a new type of tumor‐specific treatment utilizing monoclonal antibody (mAb)‐photosensitizer conjugates and near‐infrared (NIR) light irradiation. One potential PIT target, the type I transmembrane protein TROP2, is expressed at high levels in many cancers, includi...

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Bibliographic Details
Main Authors: Takashi Nishimura, Makoto Mitsunaga, Ryoichi Sawada, Masayuki Saruta, Hisataka Kobayashi, Noriko Matsumoto, Toru Kanke, Hiroyuki Yanai, Koji Nakamura
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Cancer Medicine
Subjects:
antibody‐drug conjugates
molecular‐targeted therapy
near‐infrared
photoimmunotherapy
TROP2
Online Access:https://doi.org/10.1002/cam4.2658

Internet

https://doi.org/10.1002/cam4.2658

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