CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain

CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain

Protons have been discovered to play a role in neuronal signaling, but current methods to measure pH in the brain of animal models are limited. Here the authors develop a miniaturized proton image sensor that fits into a living mouse brain and can measure pH changes at micrometer and millisecond res...

Full description

Bibliographic Details
Main Authors: Hiroshi Horiuchi, Masakazu Agetsuma, Junko Ishida, Yusuke Nakamura, Dennis Lawrence Cheung, Shin Nanasaki, Yasuyuki Kimura, Tatsuya Iwata, Kazuhiro Takahashi, Kazuaki Sawada, Junichi Nabekura
Format: Article
Language:English
Published: Nature Portfolio 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14571-y

Internet

https://doi.org/10.1038/s41467-020-14571-y

Similar Items