CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain
Protons have been discovered to play a role in neuronal signaling, but current methods to measure pH in the brain of animal models are limited. Here the authors develop a miniaturized proton image sensor that fits into a living mouse brain and can measure pH changes at micrometer and millisecond res...
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Bibliographic Details
| Main Authors: |
Hiroshi Horiuchi,
Masakazu Agetsuma,
Junko Ishida,
Yusuke Nakamura,
Dennis Lawrence Cheung,
Shin Nanasaki,
Yasuyuki Kimura,
Tatsuya Iwata,
Kazuhiro Takahashi,
Kazuaki Sawada,
Junichi Nabekura |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-14571-y
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