Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients

Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients

The instant blood-mediated inflammatory response (IBMIR) causes islet loss and compromises diabetes outcomes after total pancreatectomy with islet autotransplant (TPIAT). We previously reported a possible benefit of etanercept in maintaining insulin secretion 3 months post-TPIAT. Here, we report 2-y...

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Bibliographic Details
Main Authors: Tasneem R. Abdel-Karim, James S. Hodges, Kevan C. Herold, Timothy L. Pruett, Karthik V. Ramanathan, Bernhard J. Hering, Ty B. Dunn, Varvara A. Kirchner, Gregory J. Beilman, Melena D. Bellin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Transplant International
Subjects:
islet transplantation
diabetes
beta cell death
anti-inflammatory
TPIAT
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.12320/full

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2024.12320/full

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