Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice

Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice

Abstract Background Exposure of rodents to chronic high-fat diet (HFD) results in upregulation of inflammatory markers and proliferation of microglia within the mediobasal hypothalamus. Such hypothalamic inflammation is associated with metabolic dysfunction, central leptin resistance, and maintenanc...

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Bibliographic Details
Main Authors: Mary K. Herrick, Kristin M. Favela, Richard B. Simerly, Naji N. Abumrad, Nathan C. Bingham
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Molecular Medicine
Subjects:
Obesity
Bariatric surgery
Hypothalamus
Inflammation
Microglia
Online Access:http://link.springer.com/article/10.1186/s10020-018-0057-y

Internet

http://link.springer.com/article/10.1186/s10020-018-0057-y

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