Reliability of genomic predictions of complex human phenotypes

Abstract Genome-wide association studies have helped us identify a wealth of genetic variants associated with complex human phenotypes. Because most variants explain a small portion of the total phenotypic variation, however, marker-based studies remain limited in their ability to predict such pheno...

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Bibliographic Details
Main Authors: Arthur Porto, Juan M. Peralta, Nicholas B. Blackburn, John Blangero
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0138-5