Effects of hippocampal aromatase overexpression on spatial learning and memory in APP/PS1 mouse model of Alzheimer's disease and related neural mechanism

Effects of hippocampal aromatase overexpression on spatial learning and memory in APP/PS1 mouse model of Alzheimer's disease and related neural mechanism

] Objective To investigate the effects of hippocampal aromatase (AROM) on spatial learning and memory, specific pathology and synaptic plasticity in APP/PS1 mouse model of Alzheimer's disease (AD mice) and explore the underlying mechanisms. Methods Western blotting was used to detect the expres...

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Bibliographic Details
Main Authors: MENG Zhaoyou, SUN Huan, LAN Zhen, LIAN Biyao, CAI Xiaoxia, LIU Zhi, WANG Xiang, ZHANG Jiqiang
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
aromatase
hippocampus
learning and memory
synaptic plasticity
alzheimer's disease
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202102073.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202102073.htm

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