Potential anti-hepatocellular carcinoma properties and mechanisms of action of clerodane diterpenes isolated from Polyalthia longifolia seeds

Abstract Diterpenes are secondary metabolites that have attracted much attention due to their potential biological activities including anti-cancer potential. The aim of the current study is to assess the anticancer potential of the six known clerodane diterpenes (1–6) isolated from Polyalthia longi...

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Main Authors: Vinay Bharadwaj Tatipamula, Chandi Vishala Thonangi, Tikam Chand Dakal, Girija Sastry Vedula, Bhanupriya Dhabhai, Haritha Polimati, Annapurna Akula, Ha Thi Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13383-y