Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy
Abstract Chemotherapy persists as the primary intervention for breast cancer, with chemoresistance posing the principal obstacle to successful treatment. Herein, we show that cartilage oligomeric matrix protein (COMP) expression leads to increased cancer cell survival and attenuated apoptosis under...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-024-06872-7 |