Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy

Abstract Chemotherapy persists as the primary intervention for breast cancer, with chemoresistance posing the principal obstacle to successful treatment. Herein, we show that cartilage oligomeric matrix protein (COMP) expression leads to increased cancer cell survival and attenuated apoptosis under...

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Bibliographic Details
Main Authors: Veroniaina Hanitrarimalala, Izabela Bednarska, Takashi Murakami, Konstantinos S. Papadakos, Anna M. Blom
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06872-7