Hedysari Radix Praeparata Cum Melle repairs impaired intestinal barrier function and alleviates colitis-associated colorectal cancer via remodeling gut microbiota and metabolism

Hedysari Radix Praeparata Cum Melle repairs impaired intestinal barrier function and alleviates colitis-associated colorectal cancer via remodeling gut microbiota and metabolism

Hedysari Radix Praeparata Cum Melle (HR) has a potential to decrease the risk of chronic colorectal inflammation developing to colorectal cancer. Our study found that HR attenuated the pathological state, improved survival rate, diminished K-Ras, IL-1β, IL-6 and TNF-α levels, and increased the level...

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Bibliographic Details
Main Authors: Yugui Zhang, Yuefeng Li, Tiantian Bian, Yujing Sun, Zhuanhong Zhang, Ting Liu, Feiyun Gao, Yanjun Wang, Rui Cao, Erdan Xin, Xingke Yan
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Functional Foods
Subjects:
Hedysari Radix Praeparata Cum Melle
Colitis-associated colorectal cancer
Gut microbiota
Metabolites
Intestinal barrier function
Mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623003481

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http://www.sciencedirect.com/science/article/pii/S1756464623003481

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