Population structure and pharmacogenomic risk stratification in the United States

Population structure and pharmacogenomic risk stratification in the United States

Abstract Background Pharmacogenomic (PGx) variants mediate how individuals respond to medication, and response differences among racial/ethnic groups have been attributed to patterns of PGx diversity. We hypothesized that genetic ancestry (GA) would provide higher resolution for stratifying PGx risk...

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Bibliographic Details
Main Authors: Shashwat Deepali Nagar, Andrew B. Conley, I. King Jordan
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Biology
Subjects:
Population genomics
Pharmacogenomics
Precision public health
Genetic ancestry
Race
Ethnicity
Online Access:http://link.springer.com/article/10.1186/s12915-020-00875-4

Internet

http://link.springer.com/article/10.1186/s12915-020-00875-4

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