Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice

Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice

Abstract Background Compared with typical visceral fat deposits in obesity and metabolic syndrome, perirenal adipose tissue (PRAT) dysfunction is more closely linked to obesity-related chronic kidney disease (OB-CKD). The myokine irisin reportedly promotes positive outcomes in metabolic disease. Thi...

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Bibliographic Details
Main Authors: Fang Han, Chengxia Kan, Di Wu, Zengguang Kuang, Hongwei Song, Youhong Luo, Le Zhang, Ningning Hou, Xiaodong Sun
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Lipids in Health and Disease
Subjects:
Obesity
Chronic kidney disease
Metabolic syndrome
Irisin
Adipose
therapeutic
Online Access:https://doi.org/10.1186/s12944-022-01727-6

Internet

https://doi.org/10.1186/s12944-022-01727-6

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