Single-cell analysis reveals X upregulation is not global in pre-gastrulation embryos
Summary: In mammals, transcriptional inactivation of one X chromosome in female compensates for the dosage of X-linked gene expression between the sexes. Additionally, it is believed that the upregulation of active X chromosome in male and female balances the dosage of X-linked gene expression relat...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222007362 |