Syzygium cumini Ameliorates Insulin Resistance and β-Cell Dysfunction via Modulation of PPARγ, Dyslipidemia, Oxidative Stress, and TNF-α in Type 2 Diabetic Rats

Syzygium cumini (SC) is well known for its anti-diabetic potential, but the mechanism underlying its amelioration of type 2 diabetes is still elusive. Therefore, for the first time, we investigated whether SC aqueous seed extract (100, 200, or 400 mg/kg) exerts any beneficial effects on insulin resi...

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Bibliographic Details
Main Authors: Ashok Kumar Sharma, Saurabh Bharti, Rajiv Kumar, Bhaskar Krishnamurthy, Jagriti Bhatia, Santosh Kumari, Dharamvir Singh Arya
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319304906