Hypothermic activity of acetaminophen; Involvement of GABAA receptor, theoretical and experimental studies

Objective(s):The mechanism of hypothermia action of acetaminophen (APAP) remains unclear even 125 years after its synthesis. Acetaminophen produces hypothermia. The mechanism of this reduction in core body temperature is not clear but evidence shows that it is not dependent on opioid and cannabinoid...

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Bibliographic Details
Main Authors: Nematollah Ahangar, Zohreh Esam, Ahmadreza Bekhradnia, Mohammad Ali Ebrahimzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_6930_fcf58649ca548cc64ed4641bd70feccd.pdf