Integrated Purification and Formulation of an Active Pharmaceutical Ingredient via Agitated Bed Crystallization and Fluidized Bed Processing

Integrated Purification and Formulation of an Active Pharmaceutical Ingredient via Agitated Bed Crystallization and Fluidized Bed Processing

Integrated API and drug product processing enable molecules with high clinical efficacy but poor physicochemical characteristics to be commercialized by direct co-processing with excipients to produce advanced multicomponent intermediates. Furthermore, developing isolation-free frameworks would enab...

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Bibliographic Details
Main Authors: Michael W. Stocker, Matthew J. Harding, Valerio Todaro, Anne Marie Healy, Steven Ferguson
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
co-processing
crystallization
fluidized bed coating
formulation
isolation-free manufacturing
pharmaceuticals
Online Access:https://www.mdpi.com/1999-4923/14/5/1058

Internet

https://www.mdpi.com/1999-4923/14/5/1058

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