Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on <i>Leishmania amazonensis</i>

Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on <i>Leishmania amazonensis</i>

Leishmaniasis is a neglected tropical disease caused by <i>Leishmania</i> species. Available therapeutic options have several limitations. The drive to develop new, more potent, and selective antileishmanial agents is thus a major goal. Herein we report the synthesis and the biological a...

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Bibliographic Details
Main Authors: Kaio Maciel de Santiago-Silva, Bruna Taciane da Silva Bortoleti, Laudicéa do Nascimento Oliveira, Fernanda Lima de Azevedo Maia, Joyce Cristina Castro, Ivete Conchon Costa, Danielle Bidóia Lazarin, James L. Wardell, Solange M. S. V. Wardell, Magaly Girão Albuquerque, Camilo Henrique da Silva Lima, Wander Rogério Pavanelli, Marcelle de Lima Ferreira Bispo, Raoni Schroeder B. Gonçalves
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antibiotics
Subjects:
4,8-dimethoxynaphthalenyl
arginase
leishmaniasis
neglected diseases
trypanosomatids
trypanothione reductase
Online Access:https://www.mdpi.com/2079-6382/11/10/1402

Internet

https://www.mdpi.com/2079-6382/11/10/1402

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