A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population.

Certolizumab pegol (CZP) is a PEGylated Fc-free tumor necrosis factor (TNF) inhibitor antibody approved for use in the treatment of rheumatoid arthritis (RA), Crohn's disease, psoriatic arthritis, axial spondyloarthritis and psoriasis. In a clinical trial of patients with severe RA, CZP improve...

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Bibliografische gegevens
Hoofdauteurs: Ian R White, Sarah E Kleinstein, Christophe Praet, Chris Chamberlain, Duncan McHale, Jessica M Maia, Pingxing Xie, David B Goldstein, Thomas J Urban, Patrick R Shea
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2022-01-01
Reeks:PLoS ONE
Online toegang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261165&type=printable