Novel Alanyl-tRNA Synthetase 2 Pathogenic Variants in Leukodystrophies

The white matter disease spectrum is associated with many genetic diseases, including AARS2, CADASIL, ALD, and others. In this study, to determine the novel alanyl-tRNA synthetase 2 mutation implicated in white matter disease, several families with an autosomal recessive inheritance pattern of white...

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Bibliographic Details
Main Authors: Xingao Wang, Qun Wang, Hefei Tang, Bin Chen, Xiang Dong, Songtao Niu, Shaowu Li, Yuzhi Shi, Wei Shan, Zaiqiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01321/full