Short Term Stability Testing of Efavirenz-Loaded Solid Lipid Nanoparticle (SLN) and Nanostructured Lipid Carrier (NLC) Dispersions

Short Term Stability Testing of Efavirenz-Loaded Solid Lipid Nanoparticle (SLN) and Nanostructured Lipid Carrier (NLC) Dispersions

The short term stability of efavirenz-loaded solid lipid nanoparticle and nanostructured lipid carrier dispersions was investigated. Hot High Pressure Homogenization with the capability for scale up production was successfully used to manufacture the nanocarriers without the use of toxic organic sol...

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Bibliographic Details
Main Authors: Pedzisai A. Makoni, Kasongo Wa Kasongo, Roderick B. Walker
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Pharmaceutics
Subjects:
efavirenz
solid lipid nanoparticles
nanostructured lipid carriers
stability
Zeta potential
loading capacity
encapsulation efficiency
particle size
polydispersity index
in vitro release
Online Access:https://www.mdpi.com/1999-4923/11/8/397

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https://www.mdpi.com/1999-4923/11/8/397

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