Antigen-specific T cell activation independently of the MHC: chimeric antigen receptor (CAR)-redirected T cells.

Adoptive T cell therapy has recently shown powerful in initiating a lasting anti-tumor response with spectacular therapeutic success in some cases. Specific T cell therapy, however, is limited since a number of cancer cells are not recognized by T cells due to various mechanisms including the limite...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Hinrich eAbken, Markus eChmielewski, Andreas A. Hombach
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2013-11-01
श्रृंखला:Frontiers in Immunology
विषय:
ऑनलाइन पहुंच:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00371/full