Structural basis of a bi-functional malonyl-CoA reductase (MCR) from the photosynthetic green non-sulfur bacterium Roseiflexus castenholzii
ABSTRACT Malonyl-CoA reductase (MCR) is a NADPH-dependent bi-functional enzyme that performs alcohol dehydrogenase and aldehyde dehydrogenase (CoA-acylating) activities in the N- and C-terminal fragments, respectively. It catalyzes the two-step reduction of malonyl-CoA to 3-hydroxypropionate (3-HP),...
Main Authors: | Xin Zhang, Jiyu Xin, Zhiguo Wang, Wenping Wu, Yutong Liu, Zhenzhen Min, Yueyong Xin, Bing Liu, Jun He, Xingwei Zhang, Xiaoling Xu |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-08-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.03233-22 |
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