Programming conformational cooperativity to regulate allosteric protein-oligonucleotide signal transduction

Abstract Conformational cooperativity is a universal molecular effect mechanism and plays a critical role in signaling pathways. However, it remains a challenge to develop artificial molecular networks regulated by conformational cooperativity, due to the difficulties in programming and controlling...

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Bibliographic Details
Main Authors: Yuan Liang, Yunkai Qie, Jing Yang, Ranfeng Wu, Shuang Cui, Yuliang Zhao, Greg J. Anderson, Guangjun Nie, Suping Li, Cheng Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40589-z