An improved total synthesis of tunicamycin V
The tunicamycins are important biochemical tools to study N-linked glycosylation and protein misfolding in cancer biochemistry fields. We reported a convergent synthesis of tunicamycin V with 21% overall yield from D-galactal. We have further optimized our original synthetic scheme by increasing the...
Main Authors: | Katsuhiko Mitachi, David Mingle, Michio Kurosu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
|
Series: | MethodsX |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2215016123000973 |
Similar Items
-
Benefits and Pitfalls of a Glycosylation Inhibitor Tunicamycin in the Therapeutic Implication of Cancers
by: Snigdha Banerjee, et al.
Published: (2024-02-01) -
An improved high-throughput screening assay for tunicamycin sensitivity in Arabidopsis seedlings
by: Maggie E McCormack, et al.
Published: (2015-08-01) -
Effects of Escitalopram on Endoplasmic Reticulum Stress and Oxidative Stress Induced by Tunicamycin
by: Lixia Yang, et al.
Published: (2021-10-01) -
Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma
by: Guohong Zhao, et al.
Published: (2020-10-01) -
Modulation of Endocannabinoid-Binding Receptors in Human Neuroblastoma Cells by Tunicamycin
by: Cinzia Rapino, et al.
Published: (2019-04-01)