Assessment of replicate bias in 454 pyrosequencing and a multi-purpose read-filtering tool

<p>Abstract</p> <p>Background</p> <p>Roche 454 pyrosequencing platform is often considered the most versatile of the Next Generation Sequencing technology platforms, permitting the sequencing of large genomes, the analysis of variations or the study of transcriptomes. A...

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Bibliographic Details
Main Authors: Klopp Christophe, Noirot Céline, Jérôme Mariette
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/4/149