Losartan Improves Adipose Tissue-Derived Stem Cell Niche by Inhibiting Transforming Growth Factor-β and Fibrosis in Skeletal Muscle Injury

Losartan Improves Adipose Tissue-Derived Stem Cell Niche by Inhibiting Transforming Growth Factor-β and Fibrosis in Skeletal Muscle Injury

Recently, adipose tissue-derived stem cells (ASCs) were emerged as an alternative, abundant, and easily accessible source of stem cell therapy. Previous studies revealed losartan (an angiotensin II type I receptor blocker) treatment promoted the healing of skeletal muscle by attenuation of the TGF-β...

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Bibliographic Details
Main Authors: Jin-Kyu Park, Mi-Ran Ki, Eun-Mi Lee, Ah-Young Kim, Sang-Young You, Seon-Young Han, Eun-Joo Lee, Il-Hwa Hong, Soon-Hak Kwon, Seong-Jin Kim, Thomas A. Rando, Kyu-Shik Jeong D.V.M., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X637055

Internet

https://doi.org/10.3727/096368912X637055

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