Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity

Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity

SuccFerr <i>(N-[4-ferrocenyl,5-5-bis (4-hydroxyphenyl)-pent-4-enyl]-succinimide)</i> has remarkable antiproliferative effects in vitro, attributed to the formation of a stabilized quinone methide. The present article reports in vivo results for a possible preclinical study. SuccFerr is l...

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Bibliographic Details
Main Authors: Feten Najlaoui, Benoit Busser, Germain Sotoing Taïwe, Pascal Pigeon, Nathalie Sturm, Diane Giovannini, Naziha Marrakchi, Ali Rhouma, Gérard Jaouen, Stéphane Gibaud, Michel De Waard
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
ferrocenyl tamoxifen derivatives
cyclodextrin
glioblastoma
anticancer drug
Online Access:https://www.mdpi.com/1420-3049/27/14/4651

Internet

https://www.mdpi.com/1420-3049/27/14/4651

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