Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.

Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.

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BACKGROUND:The Crimean-Congo hemorrhagic fever virus (CCHFV) is a segmented negative-sense RNA virus that can cause severe human disease. The World Health Organization (WHO) has listed CCHFVas a priority pathogen with an urgent need for enhanced research activities to develop effective countermeasur...

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Bibliographic Details
Main Authors: Egor P Tchesnokov, Ben A Bailey-Elkin, Brian L Mark, Matthias Götte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008283

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https://doi.org/10.1371/journal.pntd.0008283

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