Predicting Synergism of Cancer Drug Combinations Using NCI-ALMANAC Data

Drug combinations are of great interest for cancer treatment. Unfortunately, the discovery of synergistic combinations by purely experimental means is only feasible on small sets of drugs. In silico modeling methods can substantially widen this search by providing tools able to predict which of all...

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Bibliographic Details
Main Authors: Pavel Sidorov, Stefan Naulaerts, Jérémy Ariey-Bonnet, Eddy Pasquier, Pedro J. Ballester
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00509/full