DIFFERENTIATION SYNDROME IN PROMYELOCYTIC LEUKEMIA : CLINICAL PRESENTATION, PATHOGENESIS AND TREATMENT
Differentiation syndrome (DS) represents a life-threatening complication in patients with acute promyelocytic leukemia (APL) undergoing induction therapy with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO). It affects about 20-25% of all patients and there are no definitive diagnostic crit...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Mattioli1885
2011-10-01
|
Series: | Mediterranean Journal of Hematology and Infectious Diseases |
Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/300 |