Mass spectrometric identification and differentiation of botulinum neurotoxins through toxin proteomics
Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. There are seven known serotypes of BoNT, A–G, defined by their response to antisera. Many serotypes are distinguished into differing subtypes based on amino acid sequence and immunogenic properties, and some...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2013-08-01
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Series: | Reviews in Analytical Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1515/revac-2013-0013 |