Mass spectrometric identification and differentiation of botulinum neurotoxins through toxin proteomics

Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. There are seven known serotypes of BoNT, A–G, defined by their response to antisera. Many serotypes are distinguished into differing subtypes based on amino acid sequence and immunogenic properties, and some...

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Bibliographic Details
Main Authors: Kalb Suzanne R., Barr John R.
Format: Article
Language:English
Published: De Gruyter 2013-08-01
Series:Reviews in Analytical Chemistry
Subjects:
Online Access:https://doi.org/10.1515/revac-2013-0013