A self-organizing state-space-model approach for parameter estimation in hodgkin-huxley-type models of single neurons.

Traditional approaches to the problem of parameter estimation in biophysical models of neurons and neural networks usually adopt a global search algorithm (for example, an evolutionary algorithm), often in combination with a local search method (such as gradient descent) in order to minimize the val...

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Bibliographic Details
Main Authors: Dimitrios V Vavoulis, Volko A Straub, John A D Aston, Jianfeng Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3291554?pdf=render