Bw4 ligand and direct T-cell receptor binding induced selection on HLA A and B alleles
IntroductionThe HLA region is the hallmark of balancing selection, argued to be driven by the pressure to present a wide variety of viral epitopes. As such selection on the peptide-binding positions has been proposed to drive HLA population genetics. MHC molecules also directly binds to the T-Cell R...
| Päätekijät: | , , |
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| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Frontiers Media S.A.
2023-11-01
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| Sarja: | Frontiers in Immunology |
| Aiheet: | |
| Linkit: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236080/full |