LymphoTrack Is Equally Sensitive as PCR GeneScan and Sanger Sequencing for Detection of Clonal Rearrangements in ALL Patients

Monoclonal rearrangements of immunoglobulin (Ig) genes and T-cell receptor (TCR) genes are used for minimal measurable disease in acute lymphoblastic leukemia (ALL). The golden standard for screening of gene rearrangements in ALL has been PCR GeneScan and Sanger sequencing, which are laborsome and t...

Full description

Bibliographic Details
Main Authors: Karin Paulsen, Millaray Marincevic, Lucia Cavelier, Peter Hollander, Rose-Marie Amini
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/6/1389