Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification

Abstract Background Osteoporosis (OP) is a major and growing public health problem characterized by decreased bone mineral density and destroyed bone microarchitecture. Previous studies found that Lycium Chinense Mill (LC) has a potent role in inhibiting bone loss. Kukoamine A (KuA), a bioactive com...

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Bibliographic Details
Main Authors: Liying Luo, Zhiyuan Guan, Xiao Jin, Zhiqiang Guan, Yanyun Jiang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-023-00625-6