Molecular mechanisms in colitis-associated colorectal cancer

Abstract Sustained chronic inflammation of the large intestine leads to tissue damage and repair, which is associated with an increased incidence of colitis-associated colorectal cancer (CAC). The genetic makeup of CAC is somewhat similar to sporadic colorectal carcinoma (sCRC), but there are differ...

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Bibliographic Details
Main Authors: Royce W. Zhou, Noam Harpaz, Steven H. Itzkowitz, Ramon E. Parsons
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-023-00492-0