Simultaneous transcriptional profiling of bacteria and their host cells.

Simultaneous transcriptional profiling of bacteria and their host cells.

We developed an RNA-Seq-based method to simultaneously capture prokaryotic and eukaryotic expression profiles of cells infected with intracellular bacteria. As proof of principle, this method was applied to Chlamydia trachomatis-infected epithelial cell monolayers in vitro, successfully obtaining tr...

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Bibliographic Details
Main Authors: Michael S Humphrys, Todd Creasy, Yezhou Sun, Amol C Shetty, Marcus C Chibucos, Elliott F Drabek, Claire M Fraser, Umar Farooq, Naomi Sengamalay, Sandy Ott, Huizhong Shou, Patrik M Bavoil, Anup Mahurkar, Garry S A Myers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3851178?pdf=render

Internet

http://europepmc.org/articles/PMC3851178?pdf=render

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