A single-cell based precision medicine approach using glioblastoma patient-specific models

A single-cell based precision medicine approach using glioblastoma patient-specific models

Abstract Glioblastoma (GBM) is a heterogeneous tumor made up of cell states that evolve over time. Here, we modeled tumor evolutionary trajectories during standard-of-care treatment using multi-omic single-cell analysis of a primary tumor sample, corresponding mouse xenografts subjected to standard...

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Bibliographic Details
Main Authors: James H. Park, Abdullah H. Feroze, Samuel N. Emerson, Anca B. Mihalas, C. Dirk Keene, Patrick J. Cimino, Adrian Lopez Garcia de Lomana, Kavya Kannan, Wei-Ju Wu, Serdar Turkarslan, Nitin S. Baliga, Anoop P. Patel
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00294-4

Internet

https://doi.org/10.1038/s41698-022-00294-4

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