Iron is increased in the brains of ageing mice lacking the neurofilament light gene.

There has been strong interest in the role of metals in neurodegeneration, and how ageing may predispose the brain to related diseases such as Alzheimer's disease. Recent work has also highlighted a potential interaction between different metal species and various components of the cytoskeletal...

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Bibliographic Details
Main Authors: James C Vickers, Anna E King, Graeme H McCormack, Aidan D Bindoff, Paul A Adlard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224169