Joint effect of multiple common SNPs predicts melanoma susceptibility.

Single genetic variants discovered so far have been only weakly associated with melanoma. This study aims to use multiple single nucleotide polymorphisms (SNPs) jointly to obtain a larger genetic effect and to improve the predictive value of a conventional phenotypic model. We analyzed 11 SNPs that...

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Bibliographic Details
Main Authors: Shenying Fang, Jiali Han, Mingfeng Zhang, Li-e Wang, Qingyi Wei, Christopher I Amos, Jeffrey E Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877376?pdf=render