Soluble Spike DNA Vaccine Provides Long-Term Protective Immunity against SARS-CoV-2 in Mice and Nonhuman Primates

Soluble Spike DNA Vaccine Provides Long-Term Protective Immunity against SARS-CoV-2 in Mice and Nonhuman Primates

The unprecedented and rapid spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) has motivated the need for a rapidly producible and scalable vaccine. Here, we developed a synthetic soluble SARS-CoV-2 spike (S) DNA-based vaccine candidate, GX-19. In mice, immunization with GX-19 el...

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Bibliographic Details
Main Authors: Yong Bok Seo, You Suk Suh, Ji In Ryu, Hwanhee Jang, Hanseul Oh, Bon-Sang Koo, Sang-Hwan Seo, Jung Joo Hong, Manki Song, Sung-Joo Kim, Young Chul Sung
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Vaccines
Subjects:
COVID-19
DNA vaccine
Online Access:https://www.mdpi.com/2076-393X/9/4/307

Internet

https://www.mdpi.com/2076-393X/9/4/307

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